Understanding Gout and Hyperuricemia Gout is an inflammatory disease caused by the deposition of monosodium urate crystals in joints due to hyperuricemia. Uric acid, formed from purines, can exceed its solubility leading to crystal formation. Factors like diet, dehydration, alcohol consumption, genetic predisposition or medications can contribute to hyperuricemia.
Treatment and Complications of Gout Gouty attacks cause severe pain and swelling in joints which are treated with NSAIDs or corticosteroids. Long-term management involves modifying the diet (hydration & avoiding certain foods), using medications that decrease uric acid levels such as xanthine oxidase inhibitors or uricosurics. Chronic gout leads to joint tissue destruction and permanent deformity along with complications like kidney stones.