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Langerhans cell histiocytosis (Year of the Zebra)

Understanding Langerhans Cell Histiocytosis Langerhans cell histiocytosis is a disorder where mutated immune cells infiltrate the body, causing damage and forming lesions. Symptoms vary depending on the affected body systems, ranging from skin rashes to lung problems and bone pain.

Diagnosis of Langerhans Cell Histiocytosis The diagnosis involves blood tests, X-rays, CT scans or MRIs to detect abnormalities in the brain and pituitary gland. Biopsy confirms the condition by showing abnormal longer Han cells in affected sites.

Treatment Options for Langerhans Cell Histiocytosis Treatment depends on which organs are affected; it may involve observation, localized treatments like surgery or steroid injections for isolated lesions, or systemic therapy with chemotherapy or targeted molecules for multi-system disease.