Understanding Substance Abuse Disorder Substance abuse disorder affects millions globally, ranging from drug use patterns to addiction. Addictive substances alter brain chemistry by increasing pleasure and calmness signals, leading to tolerance and dependence. The reward pathway in the brain is exploited by addictive drugs, impacting decision-making and driving impulsive behaviors.
Factors Influencing Addiction Risk Addiction susceptibility varies due to genetics and life experiences; trauma and early substance use increase risks. Different drugs vary in addictiveness based on chemical structure; faster-acting substances like heroin are more addictive than morphine. Genetic factors can influence addiction risk or resistance through sensitivity to certain substances.